MBP anticorps

N° du produit ABIN1110156

Cet anticorps anti-MBP est un anticorps Poulet détectant MBP dans WB et IF. Adapté pour Humain, Souris, Rat et Boeuf (Vache).

Aperçu rapide pour MBP anticorps (ABIN1110156)

Antigène: MBP (Myelin Basic Protein (MBP))

Reactivité: Humain, Souris, Rat, Boeuf (Vache)

Hôte: Poulet

Conjugué: Cet anticorp MBP est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-MBP anticorps

Purification: Aff - Purified

Immunogène: Mixture of 3 MBP peptides which are the different forms of the protein which are alternate transcription from a single gene.

Isotype: IgY

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Stock: -20 °C

Détails sur MBP

Antigène: MBP (Myelin Basic Protein (MBP))

Autre désignation: Myelin Basic Protein

Sujet: Myelin basic protein is reported to account for about 30 of the proteins in myelin found in the central nervous system. It can induce experimental allergic encephalomyelitis (EAE), a T-lymphocyte mediated disease due to delayed-type hypersensitivity, though each animal species appears to respond to a different fragment of the 170 amino acid polypeptide. Four different isoforms have been identified through cDNA cloning. All four of these variants are identical except for the insertion or deletion of two peptide fragments encoded by exons 2 and 5. Myelin basic protein is reported to be expressed in oligodendrocytes, myelin of white matter in the brain and spinal cord and in peripheral nerves, though it is expressed less abundantly in gray matter.